# Ionis Pharmaceuticals (IONS): value investors who own it

2 value investors held Ionis Pharmaceuticals in their Q3 2026 13F, led by Tweedy, Browne, Horizon Kinetics.

## 13F holders

| Manager | Portfolio | Value | Change | Quarters held |
| --- | --- | --- | --- | --- |
| Tweedy, Browne | 13.7% | $181m | Added +0.2% | 18 |
| Horizon Kinetics | 0.0% | $865k | Trimmed -4.6% | 30 |

## Directors buying and selling (Form 4, last 12 months)

| Date | Who | Role | Bought or sold | Shares | Value |
| --- | --- | --- | --- | --- | --- |
| 2026-10-16 | Devers Shannon L. | EVP, Chief Human Resources Ofc | Sold | 1357 | $59k |
| 2026-10-16 | Swayze Eric | EVP Research | Sold | 53 | $2k |
| 2026-07-31 | Hayden Michael R | Director | Bought | 5000 | $258k |
| 2026-07-30 | Hayden Michael R | Director | Bought | 15000 | $801k |

## Fund holders

| Fund | Manager | Weight | Value | As at |
| --- | --- | --- | --- | --- |
| Tweedy, Browne International Value Fund | Tweedy, Browne | 3.3% | $138m | 2026-06-30 |
| Tweedy, Browne International Value Fund II | Tweedy, Browne | 2.5% | $4.0m | 2026-06-30 |

Source: SEC filings, via moatshark (https://www.moatshark.com/s/ions). Values traded and returns are estimates. Not investment advice. Built 2026-10-21.
